![ASCO-GI 2023: Zolbetuximab + mFOLFOX6 as first-line (1L) treatment for patients (pts) with claudin-18.2+ (CLDN18.2+) / HER2− locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary results ... ASCO-GI 2023: Zolbetuximab + mFOLFOX6 as first-line (1L) treatment for patients (pts) with claudin-18.2+ (CLDN18.2+) / HER2− locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary results ...](https://larvolclin.s3.us-west-2.amazonaws.com/resize_1674280542174156690263cb7e5ed8d0f.png)
ASCO-GI 2023: Zolbetuximab + mFOLFOX6 as first-line (1L) treatment for patients (pts) with claudin-18.2+ (CLDN18.2+) / HER2− locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary results ...
![ASCO-GI 2023: Zolbetuximab + mFOLFOX6 as first-line (1L) treatment for patients (pts) with claudin-18.2+ (CLDN18.2+) / HER2− locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary results ... ASCO-GI 2023: Zolbetuximab + mFOLFOX6 as first-line (1L) treatment for patients (pts) with claudin-18.2+ (CLDN18.2+) / HER2− locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary results ...](https://larvolclin.s3.us-west-2.amazonaws.com/resize_1674281347210780159363cb8183e7565.png)
ASCO-GI 2023: Zolbetuximab + mFOLFOX6 as first-line (1L) treatment for patients (pts) with claudin-18.2+ (CLDN18.2+) / HER2− locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary results ...
Astellas to Present Positive Findings from Phase 3 SPOTLIGHT Trial of Zolbetuximab during 2023 ASCO GI Cancers
![ASCO-GI 2023: Zolbetuximab + mFOLFOX6 as first-line (1L) treatment for patients (pts) with claudin-18.2+ (CLDN18.2+) / HER2− locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary results ... ASCO-GI 2023: Zolbetuximab + mFOLFOX6 as first-line (1L) treatment for patients (pts) with claudin-18.2+ (CLDN18.2+) / HER2− locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary results ...](https://larvolclin.s3.us-west-2.amazonaws.com/resize_167428100958809908863cb8031a00ac.png)
ASCO-GI 2023: Zolbetuximab + mFOLFOX6 as first-line (1L) treatment for patients (pts) with claudin-18.2+ (CLDN18.2+) / HER2− locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary results ...
![FAST: a randomised phase II study of zolbetuximab (IMAB362) plus EOX versus EOX alone for first-line treatment of advanced CLDN18.2-positive gastric and gastro-oesophageal adenocarcinoma - Annals of Oncology FAST: a randomised phase II study of zolbetuximab (IMAB362) plus EOX versus EOX alone for first-line treatment of advanced CLDN18.2-positive gastric and gastro-oesophageal adenocarcinoma - Annals of Oncology](https://www.annalsofoncology.org/cms/asset/82729b92-7fdd-4c00-bf37-a5d517fbb18b/gr1.jpg)
FAST: a randomised phase II study of zolbetuximab (IMAB362) plus EOX versus EOX alone for first-line treatment of advanced CLDN18.2-positive gastric and gastro-oesophageal adenocarcinoma - Annals of Oncology
![Zolbetuximab plus mFOLFOX6 successful in CLDN18.2-positive subgroup of gastric cancer - Medical Conferences Zolbetuximab plus mFOLFOX6 successful in CLDN18.2-positive subgroup of gastric cancer - Medical Conferences](https://conferences.medicom-publishers.com/wp-content/uploads/2023/03/ASCO-GI-2023_Figure-Higher-PFS-for-patients-on-zolbetuximab.png)
Zolbetuximab plus mFOLFOX6 successful in CLDN18.2-positive subgroup of gastric cancer - Medical Conferences
![Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind ... Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind ...](https://www.thelancet.com/cms/attachment/52e8d146-125c-4da8-ab61-22b4597b34fc/gr3a_lrg.jpg)
Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind ...
![ASCO-GI 2023: Zolbetuximab + mFOLFOX6 as first-line (1L) treatment for patients (pts) with claudin-18.2+ (CLDN18.2+) / HER2− locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary results ... ASCO-GI 2023: Zolbetuximab + mFOLFOX6 as first-line (1L) treatment for patients (pts) with claudin-18.2+ (CLDN18.2+) / HER2− locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary results ...](https://larvolclin.s3.us-west-2.amazonaws.com/resize_167428074830915951463cb7f2ca554f.png)
ASCO-GI 2023: Zolbetuximab + mFOLFOX6 as first-line (1L) treatment for patients (pts) with claudin-18.2+ (CLDN18.2+) / HER2− locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary results ...
![FAST: a randomised phase II study of zolbetuximab (IMAB362) plus EOX versus EOX alone for first-line treatment of advanced CLDN18.2-positive gastric and gastro-oesophageal adenocarcinoma - ScienceDirect FAST: a randomised phase II study of zolbetuximab (IMAB362) plus EOX versus EOX alone for first-line treatment of advanced CLDN18.2-positive gastric and gastro-oesophageal adenocarcinoma - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0923753421001228-gr2ac.jpg)
FAST: a randomised phase II study of zolbetuximab (IMAB362) plus EOX versus EOX alone for first-line treatment of advanced CLDN18.2-positive gastric and gastro-oesophageal adenocarcinoma - ScienceDirect
![FAST: a randomised phase II study of zolbetuximab (IMAB362) plus EOX versus EOX alone for first-line treatment of advanced CLDN18.2-positive gastric and gastro-oesophageal adenocarcinoma - ScienceDirect FAST: a randomised phase II study of zolbetuximab (IMAB362) plus EOX versus EOX alone for first-line treatment of advanced CLDN18.2-positive gastric and gastro-oesophageal adenocarcinoma - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0923753421001228-gr2df.jpg)
FAST: a randomised phase II study of zolbetuximab (IMAB362) plus EOX versus EOX alone for first-line treatment of advanced CLDN18.2-positive gastric and gastro-oesophageal adenocarcinoma - ScienceDirect
![Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind, phase 3 ... Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind, phase 3 ...](https://www.thelancet.com/cms/attachment/d406b4a5-7c36-496c-83be-e053932a2054/gr3b_lrg.jpg)
Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind, phase 3 ...
![Arturo Loaiza-Bonilla, MD MSEd on Twitter: "Very excited to participate as PI in this novel study bringing #innovative #pancreaticcancer #clinicaltrials to our patients at @CancerCenter !! #cancerresearch #precisionmedicine #targetedtherapy #biomarkers ... Arturo Loaiza-Bonilla, MD MSEd on Twitter: "Very excited to participate as PI in this novel study bringing #innovative #pancreaticcancer #clinicaltrials to our patients at @CancerCenter !! #cancerresearch #precisionmedicine #targetedtherapy #biomarkers ...](https://pbs.twimg.com/media/D8hEy4IXsAAL-4A.jpg:large)
Arturo Loaiza-Bonilla, MD MSEd on Twitter: "Very excited to participate as PI in this novel study bringing #innovative #pancreaticcancer #clinicaltrials to our patients at @CancerCenter !! #cancerresearch #precisionmedicine #targetedtherapy #biomarkers ...
![Pamela Kunz, MD on Twitter: "#GI23 📢Oral Abstract Session A starting now CLAUDIN 18.2 getting lots of air time today. 🔦SPOTLIGHT Trial: Zolbetuximab + mFOLFOX vs. PBO + mFOLFOX in pts with Pamela Kunz, MD on Twitter: "#GI23 📢Oral Abstract Session A starting now CLAUDIN 18.2 getting lots of air time today. 🔦SPOTLIGHT Trial: Zolbetuximab + mFOLFOX vs. PBO + mFOLFOX in pts with](https://pbs.twimg.com/media/Fm3a3YGaYAAXQz_.jpg:large)
Pamela Kunz, MD on Twitter: "#GI23 📢Oral Abstract Session A starting now CLAUDIN 18.2 getting lots of air time today. 🔦SPOTLIGHT Trial: Zolbetuximab + mFOLFOX vs. PBO + mFOLFOX in pts with
![Zolbetuximab Meets Primary Endpoint in Phase 3 SPOTLIGHT Trial in Treatment in Gastric Cancers - Onco'Zine Zolbetuximab Meets Primary Endpoint in Phase 3 SPOTLIGHT Trial in Treatment in Gastric Cancers - Onco'Zine](https://www.oncozine.com/wp-content/uploads/2019/01/Fotolia_195507244_Subscription_Monthly_M.jpg)
Zolbetuximab Meets Primary Endpoint in Phase 3 SPOTLIGHT Trial in Treatment in Gastric Cancers - Onco'Zine
![Results from Astellas' Phase 3 SPOTLIGHT Trial of Investigational Zolbetuximab Published in The Lancet Results from Astellas' Phase 3 SPOTLIGHT Trial of Investigational Zolbetuximab Published in The Lancet](https://mma.prnewswire.com/media/458529/Astellas_Logo.jpg?p=twitter)
Results from Astellas' Phase 3 SPOTLIGHT Trial of Investigational Zolbetuximab Published in The Lancet
![SPOTLIGHT: zolbetuximab plus chemotherapy prolongs PFS and OS in CLDN18.2+ metastatic gastric cancer | VJOncology SPOTLIGHT: zolbetuximab plus chemotherapy prolongs PFS and OS in CLDN18.2+ metastatic gastric cancer | VJOncology](https://www.vjoncology.com/wp-content/uploads/2023/03/GettyImages-1265549997-maagdarmstelsel-e1627370966944-1024x769-1.jpg)
SPOTLIGHT: zolbetuximab plus chemotherapy prolongs PFS and OS in CLDN18.2+ metastatic gastric cancer | VJOncology
![Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind, phase 3 ... Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind, phase 3 ...](https://www.thelancet.com/cms/attachment/461a8a65-ddc8-4b4f-aa8f-a6dc22dc4bc9/gr1_lrg.jpg)